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Artal Group S A

Portfolio

Holdings

Most recent quarter

% of Total Shares

% of Total Assets

Shares

Book Value

Market Price Value

Fundamental Score

Achilles Therapeutics PLC ADR

2024-03-31

1.769

0.024

755.3k

$2.5m

$629.2k

2024-03-31

1.196

0.114

1m

$1.6m

$3.5m

2023-12-31

2.265

0.064

1m

$1.5m

$2.8m

Adaptimmune Therapeutics Plc

2024-03-31

0.499

0.038

1.1m

$107.7k

$1.3m

ADGI.NASDAQ

-

-

-

-

0.91

0.175

1m

-

-

ADGI.NYSE

-

-

-

-

0.91

0.175

1m

-

-

Adverum Biotechnologies Inc

2024-03-31

3.02

0.192

3m

$26.3m

$20.6m

2024-03-31

3.723

0.43

15.6m

-$141.6m

$236.5m

Alpine Immune Sciences Inc

2024-03-31

2.054

0.586

1.1m

$5.7m

$9m

2024-03-31

5.737

0.149

6.5m

$6.9m

$4.6m

Alx Oncology Holdings

2024-03-31

1.004

0.116

500k

$1.5m

$2.7m

AMAM.NASDAQ

-

-

-

-

1.133

0.358

702.2k

-

-

AMAM.NYSE

-

-

-

-

1.272

0.372

702.2k

-

-

2024-03-31

1.913

0.233

1m

$2.1m

$4.5m

Apellis Pharmaceuticals Inc

2024-03-31

1.084

1.97

1.3m

$2.8m

$47.6m

Applied Therapeutics Inc

2024-03-31

0.832

0.017

400k

$214.8k

$1.8m

APTX.NASDAQ

-

-

-

-

9.033

0.097

6.1m

-

-

2023-09-30

6.216

0.179

4.5m

$663k

$182.9k

2023-12-31

0.723

8.095

400k

$27.5m

$174.3m

Arrowhead Pharmaceuticals Inc

2024-03-31

2.445

2.213

3m

$12.1m

$77.6m

Atara Biotherapeutics Inc

2024-03-31

1.06

0.416

1m

-$699k

$8.2m

Astria Therapeutics Inc

2024-03-31

1.61

0.317

884.2k

$5.9m

$8m

Aurinia Pharmaceuticals Inc

2024-03-31

0.696

0.333

1m

$2.4m

$5.6m

Aura Biosciences Inc

2024-03-31

1.085

0.24

410k

$1.7m

$2.8m

AXLA.NASDAQ

-

-

-

-

0.969

0.052

712.5k

-

-

Black Diamond Therapeutics Inc

2024-03-31

3.637

0.191

2m

$3.7m

$9.1m

2024-03-31

0.387

1.613

404.7k

$10.1m

$59.5m

BLU.NASDAQ

-

-

-

-

2.923

1.698

3.7m

-

-

CATB.NASDAQ

-

-

-

-

0.256

0.007

33.3k

-

-

CDAK.NASDAQ

-

-

-

-

0.543

0.005

200k

-

-

Cidara Therapeutics Inc

2024-03-31

0.252

0.01

224.6k

-$404.4k

$2.7m

Cerevel Therapeutics Holdings Inc

2024-03-31

0.909

1.534

1.6m

$5m

$67.1m

CFRX.NASDAQ

-

-

-

-

0.175

0.002

18.7k

-

-

Cullinan Oncology LLC

2024-03-31

0.635

0.152

250k

$1.8m

$4m

CHMA.NASDAQ

-

-

-

-

0.601

0.037

380k

-

-

CINC.NASDAQ

-

-

-

-

0.313

0.138

137k

-

-

Centessa Pharmaceuticals PLC ADR

2024-03-31

1.25

0.407

1.4m

$2.6m

$12.3m

Cardiff Oncology Inc

2024-03-31

1.679

0.059

750k

$1m

$1.6m

2024-03-31

1.781

0.045

105k

$168.5k

$669.9k

Crinetics Pharmaceuticals Inc

2024-03-31

1.763

1.658

1.3m

$15.4m

$60.9m

Corvus Pharmaceuticals Inc

2024-03-31

1.021

0.036

500k

$266.5k

$910k

Cyclerion Therapeutics Inc

2024-03-31

5.559

0.011

138.9k

$551.6k

$284.8k

Cytokinetics Inc

2024-03-31

1.161

3.37

1.2m

-$4.1m

$67.4m

Design Therapeutics Inc

2024-03-31

0.717

0.299

400k

$1.9m

$1.3m

Dyne Therapeutics Inc

2024-03-31

1.526

1.098

1.5m

$7.2m

$52.2m

DYNS.NASDAQ

-

-

-

-

1.697

0.207

500k

-

-

Elevation Oncology Inc

2024-03-31

2.769

0.198

1.5m

$2.1m

$4.3m

EQRX.NASDAQ

-

-

-

-

0.819

0.845

4m

-

-

2024-03-31

1.731

0.248

4.7m

$4.9m

$10.2m

Drug Manufacturers - Specialty & Generic

2024-03-31

0.325

0.519

1.1m

$3.8m

$6m

Exscientia Ltd ADR

2024-03-31

0.446

0.164

550k

$1.8m

$3.1m

Fate Therapeutics Inc

2024-03-31

2.638

0.881

2.6m

$9.7m

$8.2m

Foghorn Therapeutics Inc

2024-03-31

1.303

0.155

720.7k

-$1.2m

$3.8m

Amicus Therapeutics Inc

2024-03-31

1.385

2.118

4m

$1.7m

$40.7m

Fusion Pharmaceuticals Inc

2024-03-31

1.182

0.321

1m

$2.8m

$21.6m

Generation Bio Co

2024-03-31

4.255

0.294

2.8m

$5.6m

$6.1m

Geron Corporation

2024-03-31

1.025

0.506

5.5m

$3.1m

$25.2m

GlycoMimetics Inc

2024-03-31

13.32

0.657

8.5m

$3.8m

$2.2m

Gossamer Bio Inc

2024-03-31

5.883

0.4

13.3m

$1.5m

$14.3m

GRPH.NASDAQ

-

-

-

-

1.204

0.13

700k

-

-

Gritstone Oncology Inc

2024-03-31

0.95

0.068

1m

$121.6k

$597.9k

HARP.NASDAQ

-

-

-

-

6.095

0.493

1.3m

-

-

Hookipa Pharma Inc

2024-03-31

5.727

0.103

5.6m

$4.7m

$3.2m

IGM Biosciences Inc

2024-03-31

5.253

0.857

3.1m

$8.3m

$19.4m

Ikena Oncology Inc

2024-03-31

2.071

0.066

999.5k

$3.2m

$1.6m

2024-03-31

1.029

0.048

850k

$2.2m

$1.3m

Immutep Ltd ADR

2023-12-31

1.137

0.098

1m

$102k

$1.9m

2024-03-31

2.858

0.113

1.2m

$1m

$1.3m

Mink Therapeutics Inc

2024-03-31

0.005

0

1.9k

-$988.66

$1.7k

ITOS.NASDAQ

-

-

-

-

1.112

0.146

400k

-

-

KLDO.NASDAQ

-

-

-

-

1.174

0.002

500.5k

-

-

KLDO.PINK

-

-

-

-

1.174

0.002

500.5k

-

-

KRON.NASDAQ

-

-

-

-

1.403

0.035

842.9k

-

-

KRYS.NASDAQ

-

-

-

-

1.249

1.272

349.6k

-

-

Kura Oncology Inc

2024-03-31

2.52

1.043

1.9m

$11.5m

$38.4m

Kymera Therapeutics Inc

2024-03-31

4.125

2.142

2.5m

$25.4m

$76.5m

Leap Therapeutics Inc

2024-03-31

1.565

0.081

4m

$4.9m

$8m

Lexicon Pharmaceuticals Inc

2024-03-31

32.52

7.188

117.5m

$93.9m

$196.3m

Lyell Immunopharma Inc

2024-03-31

0.28

0.136

700k

$1.6m

$1m

23Andme Holding Co

Diagnostics & Research

2024-03-31

0.138

0.028

661k

$256.4k

$282.9k

2024-03-31

0.75

0.014

1m

$7.6m

$2.8m

Morphic Holding Inc

2024-03-31

4.418

1.985

2.2m

$29.3m

$70.4m

Mereo BioPharma Group PLC ADR

2024-03-31

1.2

0.063

1.5m

$91.5k

$5.4m

Marinus Pharmaceuticals Inc

2024-03-31

2.688

0.259

1m

-$289k

$1.2m

Mersana Therapeutics Inc

2024-03-31

2.514

0.309

3m

$693.7k

$5.5m

MRTX.NASDAQ

-

-

-

-

2.886

3.781

2m

-

-

MTCR.NASDAQ

-

-

-

-

2.11

0.031

924.8k

-

-

2024-03-31

2.123

0.375

1m

-$42k

$5.4m

Minerva Neurosciences Inc

2024-03-31

4.682

0.099

250k

-$1.2m

$775k

2024-03-31

4.602

0.016

1.2m

$3m

$2.8m

OMEG.NASDAQ

-

-

-

-

4.225

0.318

750k

-

-

Omega Therapeutics Inc

2024-03-31

2.4

0.123

1.3m

$992.6k

$2.3m

Oric Pharmaceuticals Inc

2024-03-31

0.887

0.132

400k

$1.9m

$3m

ORTX.NASDAQ

-

-

-

-

0.98

0.037

1.8m

-

-

Oatly Group AB ADR

Consumer Defensive

2024-03-31

0.253

0.146

1.5m

$688.5k

$1.4m

Ovid Therapeutics Inc

2024-03-31

3.531

0.268

2.5m

$2.7m

$1.8m

2024-03-31

0.617

0.075

200k

$1.1m

$3.3m

PFTA_old.NASDAQ

PFTA_old.NASDAQ

-

-

-

-

1.173

0.085

380k

-

-

Portage Fintech Acquisition Corp

Financial Services

Shell Companies

2024-03-31

3.658

0.122

380k

$1.4m

$4.1m

Praxis Precision Medicines Inc

2024-03-31

2.29

0.159

1.2m

$16.1m

$48.3m

Prothena Corporation plc

2024-03-31

1.862

0.632

1m

$9.3m

$20.2m

Replimune Group Inc

2024-03-31

0.814

0.14

500k

$3m

$4m

Relay Therapeutics Inc

2024-03-31

1.37

1.638

1.6m

$9.4m

$10.6m

Cartesian Therapeutics Inc.

2024-03-31

1.711

0.209

9.1m

-$59.9m

$155m

Repare Therapeutics Inc

2024-03-31

1.649

0.17

700k

$3.6m

$2.2m

RUBY.NASDAQ

-

-

-

-

2.258

0.003

2m

-

-

RUBY.PINK

-

-

-

-

2.258

0.003

2m

-

-

Revolution Medicines Inc

2024-03-31

1.028

1.617

1.6m

$17.7m

$63.6m

Recursion Pharmaceuticals Inc

2024-03-31

0.26

0.196

450k

$765k

$3.2m

Sage Therapeutic

2024-03-31

0.834

0.729

500k

$5.8m

$5.3m

Schrodinger Inc

Health Information Services

2024-03-31

0.972

1.083

700k

$4.9m

$14.4m

2024-03-31

7.315

0.306

4.7m

$28.2m

$7.6m

SELB.NASDAQ

-

-

-

-

5.642

0.415

9.1m

-

-

SGTX.NASDAQ

-

-

-

-

0.85

0.006

276k

-

-

Solid Biosciences LLC

2024-03-31

6.514

0.848

2.5m

$13.7m

$14.6m

Silence Therapeutics PLC

2024-03-31

5.957

1.53

2.7m

$9.4m

$50.6m

Senti Biosciences Inc

2024-03-31

0.121

0.001

55.5k

$68.1k

$18.5k

SPRO.NASDAQ

-

-

-

-

0.966

0.043

500k

-

-

SQZ.NYSE

-

-

-

-

5.447

0.014

1.6m

-

-

Scholar Rock Holding Corp

2024-03-31

14.12

5.095

11.2m

$21.4m

$87.1m

Stoke Therapeutics Inc

2024-03-31

0.576

0.103

300k

$807.9k

$3.9m

SpringWorks Therapeutics Inc

2024-03-31

1.91

1.775

1.4m

$10.8m

$52m

Syros Pharmaceuticals Inc

2024-03-31

9.372

0.649

2.5m

$966.9k

$12.6m

TALS.NASDAQ

-

-

-

-

1.683

0.11

914.2k

-

-

TCRR.NASDAQ

-

-

-

-

1.91

0.067

750k

-

-

Instil Bio Inc.

2024-03-31

0.347

0.093

450k

$14.2m

$4.4m

Tango Therapeutics Inc

2024-03-31

2.054

0.444

2.1m

$5.3m

$18.7m

Taysha Gene Therapies Inc

2024-03-31

1.959

0.216

3.6m

$853.5k

$7.5m

2Seventy Bio Inc

2024-03-31

1.493

0.455

750k

$2.9m

$3m

Verve Therapeutics Inc

2024-03-31

0.667

0.327

400k

$2.7m

$2.1m

Vigil Neuroscience Inc

2024-03-31

4.819

0.157

1.8m

$4.7m

$7.2m

Vor Biopharma Inc

2024-03-31

1.465

0.06

1m

$1.8m

$908k

Wave Life Sciences Ltd

2024-03-31

2.459

0.505

3m

$772.9k

$16.4m

WW International Inc

Consumer Cyclical

Personal Services

2024-03-31

18.77

3.628

14.8m

-$208m

$18.9m

Xilio Development Inc

2024-03-31

1.219

0.008

450k

$449.1k

$402.7k

XLRN.NASDAQ

-

-

-

-

1.635

3.851

1m

-

-

Medical Distribution

2024-03-31

0.824

0.079

686.4k

$304k

$696.7k

Y mAbs Therapeutics

2024-03-31

0.916

0.109

400k

$904k

$4.5m

YMTX.NASDAQ

-

-

-

-

2.002

0.015

217.3k

-

-

Zymeworks Inc. Common Stock

2024-03-31

0.729

0.118

450k

$2.5m

$3.9m

ZYME.NYSE

-

-

-

-

0.729

0.118

450k

-

-

Trades

Buys

Report date: 2024-03-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
ATXS.NASDAQ	884.2k	-	11m	7-17	$9.08	38.0%
CRNX.NASDAQ	1.3m	-	54.4m	34-48	$43.83	30.2%
ELEV.NASDAQ	1.5m	-	4.9m	1-6	$2.85	458.8%
GRTS.NASDAQ	1m	-	2.5m	2-3	$0.58	-68.4%
PEPG.NASDAQ	200k	-	2.3m	7-18	$16.84	159.1%
STOK.NASDAQ	300k	-	1.8m	4-16	$13.12	220.8%
TNGX.NASDAQ	2.1m	-	23.5m	7-13	$8.56	16.9%

Report date: 2023-12-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
CNTA.NASDAQ	1m	-	6.7m	5-9	$8.74	69.7%
PRTA.NASDAQ	501.3k	-	19.2m	29-56	$20.26	-28.9%

Report date: 2023-06-30

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
ADAP.NASDAQ	1.1m	-	1.3m	1-2	$1.22	38.4%

Report date: 2023-03-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
ANNX.NASDAQ	1m	-	5.6m	4-8	$4.49	23.4%
GERN.NASDAQ	5.5m	-	15.8m	2-4	$4.53	113.7%
GLYC.NASDAQ	8.5m	-	19.3m	1-4	$0.27	-77.3%
SLN.NASDAQ	505k	-	5.9m	6-17	$18.21	203.0%
TSVT.NASDAQ	750k	-	8.5m	9-15	$4.03	-55.5%

Report date: 2022-12-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
AURA.NASDAQ	410k	-	5.2m	9-18	$7.01	-25.7%
SLDB.NASDAQ	909.2k	-	4.1m	0-7	$5.87	1,297.6%

Report date: 2022-09-30

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
APLS.NASDAQ	1m	-	58.9m	44-70	$36.24	-16.9%
NERV.NASDAQ	250k	-	1.4m	3-15	$3.10	23.5%

Report date: 2022-06-30

Trade					Current
Symbol	Shares	%	Total	Price Range	Price	%
CINC.NASDAQ	137k	-	2.6m	13-27	-	-
SNTI.NASDAQ	1m	-	3.7m	2-9	$0.33	-82.5%

Report date: 2021-09-30

Trade					Current
Symbol	Shares	%	Total	Price Range	Price	%
CATB.NASDAQ	33.3k	-	0.00	0-0	-	-
PFTA_old.NASDAQ	380k	-	0.00	0-0	-	-

Sells

Report date: 2023-12-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
NBTX.NASDAQ	-1m	-100.0	-6.3m	5-9	$5.46	9.2%

Report date: 2023-06-30

Trade					Current
Symbol	Shares	%	Total	Price Range	Price	%
CFRX.NASDAQ	-18.7k	-100.0	-29.8k	1-4	-	-

Report date: 2023-03-31

Trade					Current
Symbol	Shares	%	Total	Price Range	Price	%
APTX.NASDAQ	-6.1m	-100.0	-2.2m	0-1	-	-

Report date: 2022-12-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
YI.NASDAQ	-686.4k	-100.0	-1.9m	2-4	$1.02	-56.8%

Adds

Report date: 2024-03-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
ARWR.NASDAQ	2m	195.3	64.2m	27-40	$25.57	-5.3%
BGNE.NASDAQ	302.00	0.1	48.6k	133-185	$147.04	10.6%
CNTA.NASDAQ	400k	39.5	3.7m	7-12	$8.74	31.4%
DYN.NASDAQ	300k	24.6	6.7m	12-30	$34.40	179.0%
GBIO.NASDAQ	16.4k	0.6	38.6k	2-4	$2.16	33.3%
GOSS.NASDAQ	1.2m	10.4	1.3m	1-2	$1.08	42.3%
KURA.NASDAQ	151.8k	8.6	2.9m	13-24	$20.01	50.6%
MORF.NASDAQ	75k	3.5	2.5m	26-41	$31.84	22.3%
PRTA.NASDAQ	500k	99.7	14.8m	24-42	$20.26	-16.5%
SLDB.NASDAQ	1.5m	175.0	14.8m	5-15	$5.87	12.9%

Report date: 2023-12-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
ARWR.NASDAQ	1m	18,801.7	27.1m	21-32	$25.57	23.7%
BGNE.NASDAQ	546.00	0.1	98.7k	157-205	$147.04	-6.1%
CYCN.NASDAQ	552.00	0.4	1.5k	2-5	$2.05	17.1%
DYN.NASDAQ	402.8k	49.4	3.9m	6-14	$34.40	437.5%
GOSS.NASDAQ	5.6m	88.4	4.1m	0-1	$1.08	138.4%
HARP.NASDAQ	1.2m	1,204.1	0.00	0-0	-	-
IGMS.NASDAQ	578.1k	22.9	3.3m	4-9	$6.28	64.8%
KYMR.NASDAQ	725.3k	40.2	12.9m	10-27	$30.25	215.1%
SLN.NASDAQ	500k	20.0	5.6m	6-19	$18.21	196.1%
SRRK.NASDAQ	2.1m	24.3	27.3m	6-21	$7.74	24.3%
SYRS.NASDAQ	1m	69.7	3.5m	2-8	$5.03	140.6%
WVE.NASDAQ	1m	50.4	5.3m	4-7	$5.47	37.4%

Report date: 2023-09-30

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
APLS.NASDAQ	614.5k	58.5	27.4m	20-92	$36.24	82.8%
CRIS.NASDAQ	40k	61.5	29.7k	0-7	$6.38	1,578.9%
CYTK.NASDAQ	102.8k	7.3	3.4m	29-37	$55.51	91.7%
GOSS.NASDAQ	3.3m	111.3	3.8m	1-2	$1.08	41.7%
HARP.NASDAQ	90k	900.0	200.9k	1-9	-	-
RVMD.NASDAQ	128.1k	5.3	3.7m	25-36	$37.53	52.5%
SLN.NASDAQ	800k	47.1	5.8m	5-11	$18.21	276.2%
TSHA.NASDAQ	2.2m	154.2	4.1m	1-4	$2.07	237.7%

Report date: 2023-06-30

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
ALVR.NASDAQ	1m	18.3	4.2m	3-6	$0.70	-75.9%
BDTX.NASDAQ	400k	24.3	814.5k	1-7	$4.47	212.6%
CYTK.NASDAQ	49k	3.6	1.8m	32-41	$55.51	71.8%
DYN.NASDAQ	282.4k	53.0	3.3m	8-15	$34.40	327.9%
FOLD.NASDAQ	1m	29.4	12.2m	11-14	$10.02	-5.0%
HOOK.NASDAQ	3.8m	206.4	4.1m	1-2	$0.57	-16.9%
IGMS.NASDAQ	12.2k	0.5	139k	9-18	$6.28	-26.2%
IKNA.NASDAQ	300k	19.4	1.7m	3-8	$1.66	-49.2%
KURA.NASDAQ	300k	17.5	3.5m	9-14	$20.01	110.9%
LXRX.NASDAQ	27.7m	30.9	73.4m	2-4	$1.67	-19.7%
MORF.NASDAQ	326k	18.0	16.8m	34-63	$31.84	-6.1%
MRSN.NASDAQ	813.7k	36.7	4.7m	3-10	$1.83	-38.5%
MRTX.NASDAQ	517.4k	33.7	21.2m	36-51	-	-
RVMD.NASDAQ	330.6k	16.0	8m	20-27	$37.53	87.8%
SELB.NASDAQ	4.2m	87.1	5m	1-1	-	-
SLN.NASDAQ	1.1m	236.6	7.2m	5-8	$18.21	300.7%
SRRK.NASDAQ	31.5k	0.4	238.5k	6-10	$7.74	39.2%

Report date: 2023-03-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
AGEN.NASDAQ	1.1m	7.8	2.4m	1-3	$15.13	973.0%
APLS.NASDAQ	316.3k	35.1	18.2m	45-71	$36.24	-19.3%
CERE.NASDAQ	14.4k	0.8	424.5k	23-36	$40.96	81.0%
CYTK.NASDAQ	367k	36.7	14.9m	33-46	$55.51	68.4%
ERAS.NASDAQ	10.5k	0.2	38.2k	3-5	$2.17	-18.1%
FUSN.NASDAQ	1.2m	163.3	4.8m	3-5	$21.55	635.5%
IGMS.NASDAQ	59.9k	2.4	1.2m	14-28	$6.28	-54.0%
KRYS.NASDAQ	12k	3.0	949.1k	70-90	-	-
KURA.NASDAQ	18k	1.1	225.3k	10-15	$20.01	94.3%
MRSN.NASDAQ	15.7k	0.7	88.6k	4-7	$1.83	-53.3%
OMGA.NASDAQ	259.5k	11.4	1.8m	5-12	$1.78	-62.9%
RLAY.NASDAQ	219k	15.1	3.9m	14-23	$6.36	-56.1%
RVMD.NASDAQ	1m	107.1	26.3m	20-31	$37.53	90.5%
SRRK.NASDAQ	47.6k	0.5	483.6k	7-13	$7.74	7.9%
SYRS.NASDAQ	11.9k	0.8	46.1k	3-6	$5.03	95.0%

Report date: 2022-12-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
AGEN.NASDAQ	10.5m	262.5	26.6m	2-3	$15.13	667.3%
ARAV.NASDAQ	3.2m	248.7	4.1m	1-2	$0.04	-94.6%
ERAS.NASDAQ	1.5m	48.5	10.4m	4-9	$2.17	-43.6%
GRTS.NASDAQ	1.1m	147.5	3.1m	2-4	$0.58	-72.6%
IMUX.NASDAQ	574.7k	82.1	1.5m	1-12	$1.08	-2.7%
KURA.NASDAQ	600k	54.5	8.7m	11-17	$20.01	80.1%
KYMR.NASDAQ	500k	33.3	13.3m	19-34	$30.25	60.6%
MRTX.NASDAQ	507.7k	38.3	32.8m	36-101	-	-
SRRK.NASDAQ	230.2k	2.6	1.8m	7-10	$7.74	16.1%
TSHA.NASDAQ	400k	38.4	809.9k	1-3	$2.07	53.3%
VOR.NASDAQ	2.3m	422.8	11.5m	3-8	$0.91	-73.9%

Report date: 2022-09-30

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
AGEN.NASDAQ	1m	33.3	2.5m	2-3	$15.13	733.7%
ALPN.NASDAQ	600k	101.2	4.9m	7-10	$7.60	15.0%
ALVR.NASDAQ	3.2m	140.0	21.9m	4-9	$0.70	-81.4%
CERE.NASDAQ	500k	33.3	14.8m	24-41	$40.96	67.9%
GOSS.NASDAQ	887.6k	37.6	10.9m	7-15	$1.08	-84.2%
IGMS.NASDAQ	450k	22.5	9m	15-27	$6.28	-58.8%
KURA.NASDAQ	50k	4.8	773.4k	12-20	$20.01	71.0%
KYMR.NASDAQ	500k	50.0	13.1m	19-35	$30.25	60.1%
LXRX.NASDAQ	18.5m	26.1	51.2m	2-3	$1.67	-6.2%
MORF.NASDAQ	500k	30.3	13.8m	20-34	$31.84	55.4%
MRTX.NASDAQ	225k	20.5	16.6m	58-96	-	-
RLAY.NASDAQ	754.7k	107.8	16.5m	16-33	$6.36	-60.8%
SAGE.NASDAQ	300k	66.7	11.5m	31-44	$10.78	-65.7%
SWTX.NASDAQ	1.1m	128.2	32.9m	24-40	$36.77	53.6%
SYRS.NASDAQ	1m	266.0	1.7m	1-7	$5.03	662.1%
VIGL.NASDAQ	1.1m	103.9	8.4m	2-10	$4.03	77.5%

Report date: 2022-06-30

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
CYTK.NASDAQ	275k	27.5	11m	34-49	$55.51	65.2%
FATE.NASDAQ	600k	30.0	16.7m	17-43	$3.17	-81.5%
SELB.NASDAQ	883.2k	22.1	879.9k	1-2	-	-
SRRK.NASDAQ	6.3m	257.1	46.3m	4-15	$7.74	79.0%
SWTX.NASDAQ	50k	5.9	1.8m	14-64	$36.77	170.4%
SYRS.NASDAQ	500k	14.3	472.6k	1-1	$5.03	673.8%
WVE.NASDAQ	2m	200.0	3.8m	1-4	$5.47	371.6%

Reduces

Report date: 2024-03-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
ACHL.NASDAQ	-1.5m	-66.5	-1.6m	1-2	$0.83	4.1%
APLS.NASDAQ	-106k	-7.5	-6.7m	53-74	$36.24	-31.9%
SLN.NASDAQ	-220.3k	-7.3	-4.7m	16-28	$18.21	13.7%
SWTX.NASDAQ	-200k	-12.4	-9.2m	36-54	$36.77	3.1%
VOR.NASDAQ	-1.3m	-57.4	-2.9m	2-3	$0.91	-47.5%

Report date: 2023-12-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
APLS.NASDAQ	-243.2k	-14.6	-12.3m	36-66	$36.24	-0.2%
CYTK.NASDAQ	-304.5k	-20.1	-11m	26-88	$55.51	113.7%
FHTX.NASDAQ	-1m	-58.1	-4.3m	3-7	$5.30	86.6%
FUSN.NASDAQ	-719.5k	-41.7	-3.4m	2-10	$21.55	805.5%
IKNA.NASDAQ	-850k	-46.0	-2.3m	1-5	$1.66	62.7%
KRON.NASDAQ	-700k	-45.4	-774.5k	1-2	-	-
KURA.NASDAQ	-250k	-12.4	-2.4m	7-15	$20.01	170.0%
OMGA.NASDAQ	-1.2m	-47.7	-2.4m	1-3	$1.78	36.9%
RVMD.NASDAQ	-833.7k	-33.0	-20m	15-36	$37.53	143.1%
SWTX.NASDAQ	-201.2k	-11.1	-5.2m	18-38	$36.77	104.3%
VIGL.NASDAQ	-96.9k	-5.1	-498.7k	3-9	$4.03	41.4%
VOR.NASDAQ	-340.5k	-12.7	-702.6k	2-3	$0.91	-44.0%

Report date: 2023-09-30

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
BGNE.NASDAQ	-8.5k	-2.1	-1.6m	176-225	$147.04	-16.4%
FOLD.NASDAQ	-500k	-11.0	-6.4m	11-14	$10.02	-12.1%
INKT.NASDAQ	-226.3k	-99.2	-370.1k	1-2	$0.92	-14.8%
MORF.NASDAQ	-1.8k	-0.1	-94.9k	20-62	$31.84	60.8%
MRTX.NASDAQ	-30.9k	-1.5	-0.00	0-0	-	-
VIGL.NASDAQ	-3k	-0.2	-21.2k	5-10	$4.03	-14.0%
WVE.NASDAQ	-870.5k	-30.3	-3.9m	4-6	$5.47	54.1%

Report date: 2023-06-30

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
APLS.NASDAQ	-166.2k	-13.7	-14.2m	64-95	$36.24	-43.8%
BGNE.NASDAQ	-88.8k	-17.7	-20.4m	175-272	$147.04	-15.9%
CERE.NASDAQ	-275.6k	-14.4	-8.4m	23-36	$40.96	74.5%
CYCN.NASDAQ	-553.00	-0.4	-1.3k	0-7	$2.05	1,027.6%
FUSN.NASDAQ	-250k	-12.7	-1m	3-6	$21.55	565.1%
INKT.NASDAQ	-61.3k	-21.2	-122.7k	1-3	$0.92	8.1%
KRYS.NASDAQ	-62.4k	-15.1	-6.3m	77-132	-	-
SAGE.NASDAQ	-250k	-33.3	-12.3m	40-60	$10.78	-73.1%
SWTX.NASDAQ	-729.00	0.0	-19.1k	22-34	$36.77	64.6%
VIGL.NASDAQ	-332.1k	-14.8	-3.1m	8-11	$4.03	-49.6%
VOR.NASDAQ	-104.7k	-3.8	-480.8k	3-6	$0.91	-69.8%
WVE.NASDAQ	-129.4k	-4.3	-523.7k	3-5	$5.47	73.6%

Report date: 2023-03-31

Trade					Current
Symbol	Shares	%	Total	Price Range	Price	%
AMAM.NASDAQ	-1.4m	-67.4	-7.2m	1-13	-	-
AMAM.NYSE	-1.4m	-67.4	-0.00	0-0	-	-
BGNE.NASDAQ	-98.6k	-16.4	-23.6m	209-281	$147.04	-29.6%
FOLD.NASDAQ	-473.5k	-11.8	-5.8m	11-14	$10.02	-7.2%
GOSS.NASDAQ	-218.4k	-6.7	-418.1k	1-3	$1.08	12.5%
KYMR.NASDAQ	-194.6k	-9.7	-6.2m	24-40	$30.25	25.1%
MORF.NASDAQ	-336k	-15.6	-12.3m	25-49	$31.84	28.0%
MRTX.NASDAQ	-295k	-16.1	-13.2m	36-55	-	-
SWTX.NASDAQ	-182.6k	-9.1	-5.3m	24-34	$36.77	51.4%
TALS.NASDAQ	-1.1m	-55.7	-1.8m	1-2	-	-
VOR.NASDAQ	-82.7k	-2.9	-458.7k	5-7	$0.91	-79.8%

Report date: 2022-12-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
BGNE.NASDAQ	-50k	-7.7	-9.1m	124-233	$147.04	18.1%
BLU.NASDAQ	-2.3m	-38.3	-21.4m	8-11	-	-
CERE.NASDAQ	-100k	-5.0	-2.8m	24-34	$40.96	68.2%
KRYS.NASDAQ	-100k	-20.0	-7.4m	61-82	-	-
REPL.NASDAQ	-200k	-22.2	-4.1m	17-28	$8.11	-51.4%
SNTI.NASDAQ	-1m	-94.7	-2.4m	1-9	$0.33	-72.9%
SWTX.NASDAQ	-53.4k	-2.6	-1.3m	21-29	$36.77	74.8%
VIGL.NASDAQ	-42.2k	-1.8	-518.2k	8-17	$4.03	-50.1%

Report date: 2022-09-30

Trade					Current
Symbol	Shares	%	Total	Price Range	Price	%
BLU.NASDAQ	-1m	-14.3	-10.6m	9-13	-	-
CYTK.NASDAQ	-275k	-21.6	-13.1m	38-56	$55.51	45.5%
RUBY.NASDAQ	-1.6m	-44.8	-1.2m	0-1	-	-
YI.NASDAQ	-279.9k	-29.0	-751.6k	2-3	$1.02	-47.4%

Report date: 2022-06-30

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
AGEN.NASDAQ	-2.5m	-45.5	-4.6m	1-3	$15.13	1,110.4%
ARGX.NASDAQ	-187.5k	-31.9	-60.3m	267-384	$435.84	63.0%
BGNE.NASDAQ	-15k	-2.3	-2.3m	118-216	$147.04	24.4%
BLU.NASDAQ	-1.5m	-17.6	-12.2m	6-10	-	-
MRTX.NASDAQ	-250k	-18.5	-16m	33-91	-	-

Report date: 2021-09-30

Trade					Current
Symbol	Shares	%	Total	Price Range	Price	%
XLRN.NASDAQ	-400k	-28.6	-0.00	0-0	-	-

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