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Fidelity Advisor Biotechnology I

Portfolio

Holdings

Most recent quarter

% of Total Shares

% of Total Assets

Shares

Book Value

Market Price Value

Fundamental Score

2024-09-30

0.714

1.417

384k

$3.4m

$26.5m

AGLE.NASDAQ

-

-

-

-

1.329

0.606

479.1k

-

-

2024-09-30

5.436

0.323

4.8m

$3.9m

$4.7m

Allogene Therapeutics Inc

2024-09-30

0.99

0.282

2m

$4.5m

$4.2m

Alx Oncology Holdings

2024-09-30

0.481

0.019

253.4k

$657.3k

$448.5k

2024-09-30

1.391

0.486

423.1k

$1.1m

$6m

2024-09-30

0.743

0.308

791.6k

$1.8m

$3.8m

Astria Therapeutics Inc

2024-09-30

1.734

0.585

978.7k

$5.9m

$7.2m

Autolus Therapeutics Ltd

2024-09-30

0.729

0.348

1.9m

$3.4m

$4.5m

Aerovate Therapeutics Inc

2024-09-30

0.777

0.238

224k

$623.6k

$571.2k

Bicycle Therapeutics Ltd

2024-09-30

0.218

0.187

150.2k

$1.8m

$1.9m

Celldex Therapeutics Inc

2024-09-30

0.782

1.388

513.6k

$6m

$12.5m

Cogent Biosciences Inc

2024-09-30

1.206

0.813

1.3m

$3.7m

$10.4m

Crinetics Pharmaceuticals Inc

2024-09-30

0.74

1.327

576.3k

$5.1m

$23.3m

Cytokinetics Inc

2024-09-30

0.857

4.328

840.5k

-$99.1k

$39.1m

Edgewise Therapeutics Inc

2024-09-30

0.338

0.319

315.9k

$1.6m

$7.6m

FUSN.NASDAQ

-

-

-

-

1.361

0.775

1.1m

-

-

Monte Rosa Therapeutics Inc

2024-09-30

1.6

0.444

982.7k

$2.4m

$5.6m

Ikena Oncology Inc

2024-09-30

2.505

0.097

1.2m

$3.3m

$1.8m

2024-09-30

0.319

0.75

466.9k

$1.4m

$10.9m

Janux Therapeutics Inc

2024-09-30

0.746

1.124

391.5k

$4.3m

$18.3m

Keros Therapeutics Inc

2024-09-30

1.136

1.5

409.6k

$5.3m

$5.9m

Longboard Pharmaceuticals Inc

2024-09-30

0.736

0.46

286.2k

$2m

$17.1m

Larimar Therapeutics Inc

2024-09-30

0.823

0.229

524.8k

$1.6m

$1.9m

2024-09-30

0.761

1.383

521.2k

$5.3m

$22.8m

Nurix Therapeutics Inc

2024-08-31

1.463

1.354

1m

$5.3m

$18.9m

2024-09-30

0.532

1.779

378.1k

$6.4m

$28.9m

Oric Pharmaceuticals Inc

2024-09-30

0.825

0.324

581.7k

$2.2m

$4.6m

Cartesian Therapeutics Inc.

2024-09-30

0.661

0.177

167.9k

$5.2k

$2.8m

Scholar Rock Holding Corp

2024-09-30

0.644

0.463

513.2k

$418.8k

$20.7m

Shattuck Labs Inc

2024-09-30

2.762

0.245

1.3m

$2.5m

$1.5m

2024-09-30

0.575

0.191

986.5k

$928.2k

$2.7m

Third Harmonic Bio Inc.

2024-09-30

0.762

0.252

343.4k

$2.2m

$2.8m

Tango Therapeutics Inc

2024-09-30

0.675

0.209

724.7k

$1.5m

$2.1m

Travere Therapeutics Inc

2024-09-30

0.607

0.492

528.6k

-$185k

$9.5m

Tyra Biosciences Inc

2024-09-30

0.392

0.179

198.2k

$1.2m

$3m

Viking Therapeutics Inc

2024-09-30

0.643

2.763

716.6k

$5.8m

$28.1m

Viridian Therapeutics Inc

2024-09-30

1.82

1.653

1.4m

$12.8m

$26.2m

Xenon Pharmaceuticals Inc

2024-09-30

0.932

1.553

710.7k

$7.2m

$27.3m

Zentalis Pharmaceuticals Llc

2024-09-30

0.775

0.108

552.4k

$2.7m

$1.5m

Trades

Buys

Report date: 2024-10-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
RNAC.NASDAQ	167.9k	-	2.8m	12-26	$16.84	34.9%
TVTX.NASDAQ	528.6k	-	6.8m	8-19	$18.09	128.1%

Report date: 2024-09-30

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
THRD.NASDAQ	265.1k	-	3.2m	10-16	$8.35	-18.3%

Report date: 2024-07-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
BCYC.NASDAQ	150.2k	-	3.3m	19-27	$13.31	-30.9%

Report date: 2024-06-30

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
LRMR.NASDAQ	524.8k	-	4m	6-10	$3.66	-38.1%
SVRA.NASDAQ	666.2k	-	2.9m	3-5	$2.78	-17.6%

Report date: 2024-04-30

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
ANAB.NASDAQ	124.5k	-	2.8m	18-28	$14.21	-23.1%

Report date: 2024-02-29

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
AUTL.NASDAQ	2.8m	-	17.1m	4-7	$2.36	-37.9%

Report date: 2023-12-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
ANNX.NASDAQ	1.3m	-	3.2m	2-5	$4.83	207.6%

Adds

Report date: 2024-10-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
NRIX.NASDAQ	654.6k	171.4	15.4m	18-28	$18.24	3.5%
THRD.NASDAQ	78.2k	29.5	990.1k	10-16	$8.35	-18.3%
TNGX.NASDAQ	317.8k	78.1	2.7m	5-12	$2.93	-46.1%
VRDN.NASDAQ	49.2k	3.5	957.6k	13-25	$18.20	37.9%
XENE.NASDAQ	185.2k	35.2	7.5m	36-46	$38.41	6.7%

Report date: 2024-09-30

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
ANNX.NASDAQ	290.1k	57.8	1.7m	4-7	$4.83	8.5%
MRUS.NASDAQ	400.00	0.1	20.8k	47-59	$43.85	-6.0%
NUVL.NASDAQ	7.1k	1.9	588.9k	65-114	$76.61	18.5%
VRDN.NASDAQ	107.6k	8.4	1.7m	12-24	$18.20	53.6%

Report date: 2024-08-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
ALXO.NASDAQ	3.9k	0.4	22k	2-11	$1.77	-21.2%
MRUS.NASDAQ	47.3k	10.0	2.5m	48-61	$43.85	-7.7%
NUVL.NASDAQ	29.9k	8.8	2.3m	64-88	$76.61	19.2%

Report date: 2024-07-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
ACLX.NASDAQ	81.3k	26.9	4.5m	48-67	$69.08	44.3%
ALLK.NASDAQ	1.1m	31.8	1.2m	1-2	$0.97	43.6%
ALXO.NASDAQ	16k	1.8	154.8k	4-18	$1.77	-58.0%
ATXS.NASDAQ	195.7k	25.0	1.9m	9-13	$7.45	-13.2%
AUTL.NASDAQ	1m	54.5	4.3m	3-5	$2.36	-24.5%
IMVT.NASDAQ	32.5k	7.5	914.6k	25-32	$23.48	-4.8%
MRUS.NASDAQ	45.6k	10.7	2.4m	43-62	$43.85	2.9%
SVRA.NASDAQ	320.2k	48.1	1.4m	3-5	$2.78	-17.6%
XENE.NASDAQ	96.8k	22.6	3.8m	36-45	$38.41	8.1%

Report date: 2024-06-30

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
ALLK.NASDAQ	610.9k	19.9	725.6k	1-2	$0.97	3.7%
ALXO.NASDAQ	254.9k	39.3	3.1m	6-18	$1.77	-68.1%
ANAB.NASDAQ	118.2k	38.8	2.7m	18-27	$14.21	-23.1%

Report date: 2024-05-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
ALLK.NASDAQ	1.1m	60.3	1.4m	1-2	$0.97	-1.1%
ALLO.NASDAQ	1.5m	273.6	5.5m	2-6	$2.06	-11.0%
ANAB.NASDAQ	180.3k	144.8	4.1m	18-27	$14.21	-23.1%
GLUE.NASDAQ	350.5k	55.4	2m	4-9	$5.70	46.2%
MRUS.NASDAQ	351.5k	460.1	16m	39-62	$43.85	11.7%

Report date: 2024-03-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
VKTX.NASDAQ	8.3k	1.2	369.3k	17-99	$39.31	128.1%

Report date: 2024-02-29

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
COGT.NASDAQ	816.6k	68.1	4.9m	4-10	$7.84	113.6%
LBPH.NASDAQ	106.7k	31.5	1.7m	4-28	$59.98	1,566.1%
NUVL.NASDAQ	2.7k	0.8	206k	62-89	$76.61	23.7%
TYRA.NASDAQ	390.8k	64.6	5.8m	11-21	$15.20	43.4%
VKTX.NASDAQ	2.8k	0.4	71.7k	12-99	$39.31	234.8%

Report date: 2024-01-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
KROS.NASDAQ	40.1k	10.9	1.5m	27-59	$14.56	-46.7%
NUVL.NASDAQ	914.00	0.3	62.6k	49-81	$76.61	56.3%
TYRA.NASDAQ	368k	155.3	4.6m	11-16	$15.20	43.4%
VRDN.NASDAQ	74.8k	6.2	1.3m	12-24	$18.20	54.2%

Report date: 2023-12-31

Trade					Current
Symbol	Shares	%	Total	Price Range	Price	%
AGLE.NASDAQ	455.1k	1,896.5	0.00	0-0	-	-
ALLK.NASDAQ	929.2k	94.0	2m	1-3	$0.97	-34.3%
XENE.NASDAQ	83.1k	20.2	2.9m	28-47	$38.41	37.3%

Reduces

Report date: 2024-10-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
ALXO.NASDAQ	-670.8k	-72.6	-1.4m	1-6	$1.77	32.6%
AUTL.NASDAQ	-1m	-35.5	-4.2m	3-5	$2.36	-29.1%
TYRA.NASDAQ	-192.6k	-49.3	-4.2m	15-30	$15.20	-0.5%

Report date: 2024-09-30

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
ZNTL.NASDAQ	-114.6k	-17.2	-416.7k	3-5	$2.75	-2.8%

Report date: 2024-06-30

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
ANNX.NASDAQ	-228.1k	-31.3	-1.1m	4-7	$4.83	15.0%
COGT.NASDAQ	-340.9k	-20.4	-2.5m	6-9	$7.84	33.3%
TYRA.NASDAQ	-64.9k	-14.2	-1.1m	14-21	$15.20	7.6%

Report date: 2024-05-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
ANNX.NASDAQ	-585.9k	-44.5	-3.1m	4-8	$4.83	15.0%
COGT.NASDAQ	-342.5k	-17.0	-2.3m	6-8	$7.84	36.8%
LBPH.NASDAQ	-159.7k	-35.8	-3.1m	17-24	$59.98	262.4%
TYRA.NASDAQ	-223.1k	-32.9	-3.8m	14-20	$15.20	7.6%

Report date: 2024-04-30

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
STTK.NASDAQ	-16.1k	-1.2	-150.2k	8-12	$1.19	-85.2%
TYRA.NASDAQ	-4.8k	-0.7	-84k	12-21	$15.20	21.7%

Report date: 2024-03-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
AUTL.NASDAQ	-951.4k	-32.8	-5.9m	5-7	$2.36	-55.5%
EWTX.NASDAQ	-250.4k	-44.2	-3.9m	9-21	$24.15	168.3%
SRRK.NASDAQ	-743.8k	-59.2	-11.7m	13-19	$40.49	216.1%
STTK.NASDAQ	-63.6k	-4.6	-582.9k	7-11	$1.19	-83.0%
TYRA.NASDAQ	-312k	-31.3	-5.1m	11-21	$15.20	35.2%
XENE.NASDAQ	-66.4k	-13.4	-3m	42-51	$38.41	-8.7%

Report date: 2024-02-29

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
ATXS.NASDAQ	-286.6k	-26.8	-2.7m	5-16	$7.45	65.6%

Report date: 2024-01-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
ALXO.NASDAQ	-271.9k	-29.5	-3.1m	7-16	$1.77	-74.1%
FUSN.NASDAQ	-284.1k	-19.8	-1.9m	4-12	-	-

Report date: 2023-12-31

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
ALXO.NASDAQ	-1.5k	-0.2	-14.2k	5-16	$1.77	-62.8%
AVTE.NASDAQ	-14.3k	-6.0	-209k	9-25	$2.55	-72.9%
CLDX.NASDAQ	-560.5k	-52.2	-16.4m	22-41	$24.35	10.1%
FUSN.NASDAQ	-605.6k	-29.7	-2.9m	2-10	-	-
GLUE.NASDAQ	-432.8k	-40.6	-1.6m	2-6	$5.70	133.6%
JANX.NASDAQ	-80.8k	-17.1	-699.1k	6-12	$46.76	727.6%
LBPH.NASDAQ	-137.6k	-28.9	-685.9k	4-7	$59.98	1,566.1%
ORIC.NASDAQ	-305k	-34.4	-2.2m	5-10	$7.96	51.0%
SRRK.NASDAQ	-410.5k	-24.6	-5.1m	6-21	$40.49	550.4%
STTK.NASDAQ	-66.5k	-4.5	-181.4k	1-8	$1.19	-10.5%
TNGX.NASDAQ	-227.1k	-35.8	-1.9m	5-13	$2.93	-43.2%
TYRA.NASDAQ	-55.2k	-18.9	-715.4k	10-16	$15.20	46.4%

Report date: 2023-11-30

Trade					Current
Symbol	Shares	%	Total	$ Range	Price	%
TYRA.NASDAQ	-4.4k	-1.5	-58.9k	10-16	$15.20	46.4%

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