Support PenkePalo Alto Investors, LLC
Portfolio
Holdings
| Symbol | Name | Country | Sector | Industry | Most recent quarter | % of Total Shares | % of Total Assets | Shares | Book Value | Market Price Value | Fundamental Score | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABMD.NASDAQ | ABMD.NASDAQ | - | - | - | - | 1.088 | 9.532 | 490.7k | - | - | ||||||||||||||
| ACAD.NASDAQ | ACADIA Pharmaceuticals Inc | USA | Healthcare | Biotechnology | 2024-09-30 | 1.517 | 5.042 | 2.5m | $8.7m | $43m |
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| ACRS.NASDAQ | Aclaris Therapeutics Inc | USA | Healthcare | Diagnostics & Research | 2024-09-30 | 0.798 | 0.085 | 569.8k | $692.9k | $1.6m |
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| ALIM.NASDAQ | ALIM.NASDAQ | - | - | - | - | 2.78 | 0.046 | 200.9k | - | - | ||||||||||||||
| ANAB.NASDAQ | AnaptysBio Inc | USA | Healthcare | Biotechnology | 2024-09-30 | 2.774 | 3.673 | 843.9k | $2.3m | $11.7m |
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| BLUE.NASDAQ | Bluebird bio Inc | USA | Healthcare | Biotechnology | 2024-09-30 | 2.389 | 0.528 | 4.6m | -$139k | $36m |
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| BMRN.NASDAQ | Biomarin Pharmaceutical Inc | USA | Healthcare | Biotechnology | 2024-09-30 | 0.976 | 15.33 | 1.8m | $50.2m | $122m |
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| CLVS.NASDAQ | CLVS.NASDAQ | - | - | - | - | 3.086 | 0.421 | 4.4m | - | - | ||||||||||||||
| DRNA.NASDAQ | DRNA.NASDAQ | - | - | - | - | 1.098 | 1.041 | 855.7k | - | - | ||||||||||||||
| EHTH.NASDAQ | eHealth Inc | USA | Financial Services | Insurance Brokers | 2024-09-30 | 7.922 | 1.244 | 2.3m | $65.4m | $18.8m |
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| ELEV.NASDAQ | Elevation Oncology Inc | USA | Healthcare | Biotechnology | 2024-09-30 | 2.196 | 0.101 | 1.2m | $1.5m | $732.1k |
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| EPZM.NASDAQ | EPZM.NASDAQ | - | - | - | - | 4.024 | 0.868 | 6.7m | - | - | ||||||||||||||
| FOLD.NASDAQ | Amicus Therapeutics Inc | USA | Healthcare | Biotechnology | 2024-09-30 | 2.726 | 11.30 | 8.1m | $4.7m | $79.7m |
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| GOSS.NASDAQ | Gossamer Bio Inc | USA | Healthcare | Biotechnology | 2024-09-30 | 2.77 | 0.804 | 6.2m | $1.5m | $5.2m |
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| GRTS.NASDAQ | Gritstone Oncology Inc | USA | Healthcare | Biotechnology | 2024-06-30 | 0.716 | 0.105 | 666.1k | $103.2k | $12.6k |
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| INSM.NASDAQ | Insmed Inc | USA | Healthcare | Biotechnology | 2024-09-30 | 1.085 | 18.41 | 1.9m | $5.2m | $136.8m |
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| IOVA.NASDAQ | Iovance Biotherapeutics Inc | USA | Healthcare | Biotechnology | 2024-09-30 | 0.998 | 3.71 | 3m | $7.7m | $22.7m |
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| KPTI.NASDAQ | Karyopharm Therapeutics Inc | USA | Healthcare | Biotechnology | 2024-09-30 | 4.072 | 0.55 | 5.1m | -$6.5m | $3m |
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| KZR.NASDAQ | Kezar Life Sciences Inc | USA | Healthcare | Biotechnology | 2024-09-30 | 0.903 | 0.13 | 656.2k | $1.2m | $4.3m |
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| MGTA.NASDAQ | MGTA.NASDAQ | - | - | - | - | 0.714 | 0.048 | 432.3k | - | - | ||||||||||||||
| NVCR.NASDAQ | Novocure Ltd | USA | Healthcare | Medical Devices | 2024-09-30 | 0.541 | 1.938 | 578.1k | $1.9m | $17.9m |
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| NVRO.NYSE | Nevro Corp | USA | Healthcare | Medical Devices | 2024-09-30 | 2.003 | 0.545 | 750.3k | $5.4m | $2.9m |
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| PRTA.NASDAQ | Prothena Corporation plc | USA | Healthcare | Biotechnology | 2024-09-30 | 3.23 | 3.777 | 1.7m | $17.2m | $26.7m |
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| PRVB.NASDAQ | PRVB.NASDAQ | - | - | - | - | 0.412 | 0.352 | 390.8k | - | - | ||||||||||||||
| RLMD.NASDAQ | Relmada Therapeutics Inc | USA | Healthcare | Biotechnology | 2024-09-30 | 2.427 | 0.308 | 732.4k | $1.1m | $264.3k |
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| RVNC.NASDAQ | Revance The | USA | Healthcare | Biotechnology | 2024-09-30 | 1.537 | 1.087 | 1.6m | -$2.5m | $4.9m |
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| SAGE.NASDAQ | Sage Therapeutic | USA | Healthcare | Biotechnology | 2024-09-30 | 1.652 | 0.948 | 1m | $9.1m | $5.5m |
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| SGHT.NASDAQ | Sight Sciences Inc | USA | Healthcare | Medical Devices | 2024-09-30 | 0.349 | 0.081 | 173.7k | $327.4k | $616.9k |
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| STAA.NASDAQ | STAAR Surgical Company | USA | Healthcare | Medical Instruments & Supplies | 2024-09-30 | 2.215 | 5.268 | 1m | $9.3m | $27.2m |
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| UTHR.NASDAQ | United Therapeutics Corporation | USA | Healthcare | Biotechnology | 2024-09-30 | 0.841 | 7.841 | 395.7k | $49.8m | $142.8m |
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| VERV.NASDAQ | Verve Therapeutics Inc | USA | Healthcare | Biotechnology | 2024-09-30 | 0.716 | 0.723 | 575.8k | $3.4m | $3.3m |
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| VNDA.NASDAQ | Vanda Pharmaceuticals Inc | USA | Healthcare | Biotechnology | 2024-09-30 | 1.893 | 0.685 | 1m | $10m | $5.2m |
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| VYNE.NASDAQ | Vyne Therapeutics Inc | USA | Healthcare | Biotechnology | 2024-09-30 | 3.02 | 0.109 | 445.4k | $664.5k | $1.3m |
|
Trades
Buys
Report date: 2024-03-31
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | $ Range | Price | % |
| ACRS.NASDAQ | 569.8k | - | 679.4k | 1-2 | $2.90 | 239.0% |
| ELEV.NASDAQ | 1.3m | - | 4.3m | 1-6 | $0.56 | 10.6% |
Report date: 2023-12-31
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | $ Range | Price | % |
| BLUE.NASDAQ | 3.3m | - | 10.1m | 1-6 | $7.79 | 518.3% |
| SGHT.NASDAQ | 173.7k | - | 536.2k | 1-6 | $3.55 | 241.3% |
| VERV.NASDAQ | 575.8k | - | 7.1m | 8-20 | $5.77 | -29.8% |
| VYNE.NASDAQ | 445.4k | - | 1.3m | 2-4 | $2.97 | 36.1% |
Report date: 2023-03-31
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | $ Range | Price | % |
| RLMD.NASDAQ | 542.1k | - | 1.8m | 2-5 | $0.36 | -82.0% |
Report date: 2022-09-30
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | Price Range | Price | % |
| PRVB.NASDAQ | 390.8k | - | 1.7m | 3-6 | - | - |
Sells
Report date: 2023-03-31
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | Price Range | Price | % |
| ALIM.NASDAQ | -200.9k | -100.0 | -466.8k | 1-3 | - | - |
Report date: 2022-06-30
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | Price Range | Price | % |
| KLDO.NASDAQ | -309.6k | -100.0 | -0.00 | 0-0 | - | - |
| KLDO.PINK | -309.6k | -100.0 | -77.5k | 0-2 | - | - |
Adds
Report date: 2024-09-30
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | $ Range | Price | % |
| ACAD.NASDAQ | 105.1k | 4.3 | 1.7m | 15-19 | $17.07 | 13.2% |
| ANAB.NASDAQ | 40.3k | 5.0 | 1.3m | 24-41 | $13.89 | -41.4% |
| IOVA.NASDAQ | 925.2k | 43.7 | 8.7m | 7-13 | $7.49 | 5.3% |
| PRTA.NASDAQ | 71.5k | 4.3 | 1.5m | 16-25 | $15.40 | -0.8% |
Report date: 2024-06-30
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | $ Range | Price | % |
| ACAD.NASDAQ | 3.8k | 0.2 | 62.9k | 15-19 | $17.07 | 17.3% |
| ANAB.NASDAQ | 3.7k | 0.5 | 86.9k | 18-27 | $13.89 | -24.9% |
| BLUE.NASDAQ | 73.1k | 1.6 | 73.3k | 1-1 | $7.79 | 821.9% |
| ELEV.NASDAQ | 453.4k | 33.7 | 1.7m | 2-6 | $0.56 | -74.6% |
| PRTA.NASDAQ | 2.9k | 0.2 | 63.4k | 19-26 | $15.40 | -17.6% |
| RVNC.NASDAQ | 9k | 0.2 | 31k | 2-5 | $3.08 | 33.9% |
| SAGE.NASDAQ | 5k | 0.5 | 64.7k | 10-19 | $5.48 | -43.9% |
| STAA.NASDAQ | 2k | 0.1 | 88.9k | 37-53 | $24.97 | -33.3% |
Report date: 2024-03-31
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | $ Range | Price | % |
| ACAD.NASDAQ | 5.3k | 0.2 | 133.4k | 18-32 | $17.07 | -2.8% |
| ANAB.NASDAQ | 113k | 16.5 | 2.6m | 21-28 | $13.89 | -32.7% |
| BLUE.NASDAQ | 1.2m | 36.8 | 1.5m | 1-2 | $7.79 | 786.2% |
| GOSS.NASDAQ | 432.8k | 7.3 | 476.4k | 1-2 | $0.84 | 11.2% |
| PRTA.NASDAQ | 3.3k | 0.2 | 100.8k | 24-42 | $15.40 | -36.5% |
| RVNC.NASDAQ | 10.7k | 0.2 | 63.4k | 5-10 | $3.08 | -32.6% |
| SAGE.NASDAQ | 14.2k | 1.4 | 328.7k | 18-28 | $5.48 | -70.2% |
| STAA.NASDAQ | 2.6k | 0.2 | 85.8k | 27-41 | $24.97 | -6.3% |
Report date: 2023-12-31
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | $ Range | Price | % |
| ACAD.NASDAQ | 3.7k | 0.2 | 89.8k | 20-33 | $17.07 | -15.9% |
| ANAB.NASDAQ | 255.6k | 59.3 | 4.4m | 13-22 | $13.89 | 4.0% |
| NVRO.NYSE | 363.5k | 94.0 | 6.4m | 14-23 | $3.97 | -71.6% |
| PRTA.NASDAQ | 2.5k | 0.2 | 100k | 29-56 | $15.40 | -46.0% |
| RVNC.NASDAQ | 8.6k | 0.2 | 71k | 6-11 | $3.08 | -46.2% |
| STAA.NASDAQ | 2.1k | 0.2 | 76.4k | 30-44 | $24.97 | -17.6% |
Report date: 2023-09-30
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | $ Range | Price | % |
| GOSS.NASDAQ | 3m | 88.5 | 3.5m | 1-2 | $0.84 | 10.8% |
| SAGE.NASDAQ | 146.2k | 17.0 | 4.2m | 17-50 | $5.48 | -66.8% |
Report date: 2023-06-30
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | $ Range | Price | % |
| EHTH.NASDAQ | 50k | 1.9 | 401.8k | 5-10 | $8.04 | 67.2% |
| NVCR.NASDAQ | 545.3k | 1,663.1 | 33.8m | 40-84 | $30.97 | -22.3% |
| RLMD.NASDAQ | 190.3k | 35.1 | 523k | 2-4 | $0.36 | -82.9% |
| STAA.NASDAQ | 27.5k | 2.0 | 1.6m | 50-73 | $24.97 | -49.7% |
Report date: 2023-03-31
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | $ Range | Price | % |
| ACAD.NASDAQ | 29.4k | 1.2 | 560.3k | 16-22 | $17.07 | 8.2% |
| ANAB.NASDAQ | 200.00 | 0.0 | 4.8k | 21-31 | $13.89 | -32.3% |
| EHTH.NASDAQ | 204.9k | 8.2 | 1.6m | 5-11 | $8.04 | 72.9% |
| FOLD.NASDAQ | 30.3k | 0.3 | 373.4k | 11-14 | $9.79 | -9.4% |
| GOSS.NASDAQ | 3.4m | 9,079.2 | 6.5m | 1-3 | $0.84 | -12.1% |
| INSM.NASDAQ | 18.2k | 0.3 | 353.6k | 16-22 | $70.53 | 339.7% |
| KPTI.NASDAQ | 20.2k | 0.4 | 66.4k | 3-4 | $0.60 | -78.0% |
| PRTA.NASDAQ | 5.2k | 0.3 | 274.7k | 45-61 | $15.40 | -65.8% |
| SAGE.NASDAQ | 3k | 0.4 | 128.9k | 37-50 | $5.48 | -85.2% |
| STAA.NASDAQ | 107.2k | 8.6 | 6.9m | 49-82 | $24.97 | -49.3% |
| UTHR.NASDAQ | 2.1k | 0.3 | 517.7k | 212-279 | $360.87 | 70.6% |
Report date: 2022-12-31
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | $ Range | Price | % |
| ACAD.NASDAQ | 698.1k | 41.6 | 10.9m | 14-19 | $17.07 | 24.3% |
| EHTH.NASDAQ | 506.4k | 25.6 | 1.8m | 3-5 | $8.04 | 201.1% |
| FOLD.NASDAQ | 645.9k | 6.6 | 7.2m | 9-13 | $9.79 | 7.6% |
| INSM.NASDAQ | 30.8k | 0.5 | 597.1k | 17-23 | $70.53 | 321.3% |
| KPTI.NASDAQ | 34.1k | 0.6 | 157.7k | 2-6 | $0.60 | -75.7% |
| PRTA.NASDAQ | 8.8k | 0.5 | 515.2k | 51-66 | $15.40 | -69.7% |
| RVNC.NASDAQ | 878.5k | 19.9 | 20m | 18-31 | $3.08 | -82.9% |
| SAGE.NASDAQ | 5.1k | 0.6 | 195k | 32-44 | $5.48 | -82.9% |
| STAA.NASDAQ | 143.1k | 13.1 | 8.9m | 46-77 | $24.97 | -46.1% |
Report date: 2022-09-30
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | $ Range | Price | % |
| EHTH.NASDAQ | 323.3k | 19.5 | 2.2m | 4-10 | $8.04 | 112.1% |
Report date: 2022-06-30
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | $ Range | Price | % |
| EHTH.NASDAQ | 2.4k | 0.1 | 24.9k | 8-13 | $8.04 | 1.9% |
Report date: 2021-09-30
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | Price Range | Price | % |
| DRNA.NASDAQ | 523k | 157.2 | 0.00 | 0-0 | - | - |
Reduces
Report date: 2024-09-30
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | $ Range | Price | % |
| EHTH.NASDAQ | -2.6k | -0.1 | -11.5k | 4-6 | $8.04 | 124.6% |
| ELEV.NASDAQ | -502k | -27.9 | -744.3k | 1-3 | $0.56 | 12.8% |
| FOLD.NASDAQ | -884.5k | -9.8 | -9.6m | 9-12 | $9.79 | 4.6% |
| INSM.NASDAQ | -197.9k | -9.3 | -14.6m | 62-81 | $70.53 | 14.6% |
| RVNC.NASDAQ | -3.6m | -69.3 | -18.1m | 2-7 | $3.08 | 28.6% |
| STAA.NASDAQ | -290k | -21.0 | -10.8m | 29-50 | $24.97 | -14.5% |
Report date: 2024-06-30
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | $ Range | Price | % |
| EHTH.NASDAQ | -365.4k | -13.5 | -1.8m | 4-6 | $8.04 | 88.1% |
| FOLD.NASDAQ | -314.2k | -3.4 | -3.2m | 9-12 | $9.79 | 8.5% |
| GOSS.NASDAQ | -114.6k | -1.8 | -85.8k | 0-1 | $0.84 | 69.1% |
| INSM.NASDAQ | -2.2m | -51.6 | -88.5m | 22-71 | $70.53 | 221.8% |
Report date: 2024-03-31
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | $ Range | Price | % |
| EHTH.NASDAQ | -23.6k | -0.9 | -157.2k | 5-9 | $8.04 | 57.0% |
| FOLD.NASDAQ | -1m | -9.9 | -13.1m | 11-15 | $9.79 | -13.5% |
| INSM.NASDAQ | -1m | -19.7 | -30.4m | 25-31 | $70.53 | 181.4% |
Report date: 2023-12-31
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | $ Range | Price | % |
| FOLD.NASDAQ | -150.3k | -1.4 | -1.7m | 10-15 | $9.79 | 0.9% |
| GOSS.NASDAQ | -571.4k | -8.8 | -422.1k | 0-1 | $0.84 | 86.3% |
| INSM.NASDAQ | -377.7k | -6.4 | -9.7m | 23-32 | $70.53 | 206.1% |
| KPTI.NASDAQ | -573.6k | -10.1 | -515.2k | 1-1 | $0.60 | -3.6% |
| SAGE.NASDAQ | -14.2k | -1.4 | -282.4k | 17-23 | $5.48 | -66.8% |
| UTHR.NASDAQ | -180.1k | -31.3 | -41.5m | 210-258 | $360.87 | 71.8% |
Report date: 2023-09-30
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | $ Range | Price | % |
| UTHR.NASDAQ | -51.6k | -8.2 | -11.8m | 211-262 | $360.87 | 70.8% |
Report date: 2023-06-30
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | $ Range | Price | % |
| PRTA.NASDAQ | -6.3k | -0.4 | -404.3k | 45-80 | $15.40 | -65.8% |
| RVNC.NASDAQ | -41.6k | -0.8 | -1.2m | 25-38 | $3.08 | -87.5% |
Report date: 2023-03-31
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | $ Range | Price | % |
| BMRN.NASDAQ | -54.7k | -2.9 | -5.6m | 87-118 | $66.63 | -23.7% |
| RVNC.NASDAQ | -13.4k | -0.3 | -417.7k | 18-37 | $3.08 | -83.0% |
Report date: 2022-12-31
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | $ Range | Price | % |
| BMRN.NASDAQ | -90.4k | -4.6 | -8.4m | 81-110 | $66.63 | -17.3% |
| GRTS.NASDAQ | -1.6m | -71.4 | -4.7m | 2-4 | $0.02 | -99.1% |
| UTHR.NASDAQ | -8.1k | -1.3 | -2m | 205-283 | $360.87 | 75.7% |
| VNDA.NASDAQ | -1m | -49.8 | -10.5m | 7-11 | $4.83 | -28.2% |
Report date: 2022-09-30
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | Price Range | Price | % |
| ABMD.NASDAQ | -3.6k | -0.7 | -0.00 | 0-0 | - | - |
| BMRN.NASDAQ | -85.1k | -4.1 | -7.5m | 82-98 | $66.63 | -18.4% |
| PRTA.NASDAQ | -31.7k | -1.9 | -999.9k | 25-64 | $15.40 | -38.4% |
| STAA.NASDAQ | -9.6k | -0.9 | -826.7k | 69-112 | $24.97 | -63.9% |
| UTHR.NASDAQ | -1.2k | -0.2 | -284.6k | 202-245 | $360.87 | 79.0% |
| VNDA.NASDAQ | -325k | -13.0 | -3.4m | 9-12 | $4.83 | -48.3% |
Report date: 2022-06-30
| Trade | Current | |||||
|---|---|---|---|---|---|---|
| Symbol | Shares | % | Total | $ Range | Price | % |
| ACAD.NASDAQ | -573.6k | -25.5 | -10.8m | 12-28 | $17.07 | 39.5% |
| BMRN.NASDAQ | -78.2k | -3.7 | -6.2m | 71-87 | $66.63 | -5.8% |
| FOLD.NASDAQ | -55.9k | -0.6 | -463.3k | 6-11 | $9.79 | 65.7% |
| GOSS.NASDAQ | -6.1k | -0.3 | -47.5k | 6-10 | $0.84 | -85.0% |
| INSM.NASDAQ | -40.9k | -0.7 | -859.9k | 16-26 | $70.53 | 329.8% |
| RVNC.NASDAQ | -10.6k | -0.2 | -165.3k | 11-21 | $3.08 | -72.7% |
| SAGE.NASDAQ | -310.00 | 0.0 | -10.3k | 27-39 | $5.48 | -80.0% |
| STAA.NASDAQ | -30.4k | -2.7 | -1.9m | 49-85 | $24.97 | -49.1% |
| UTHR.NASDAQ | -18.2k | -2.8 | -3.7m | 173-243 | $360.87 | 108.3% |
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