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Siren, L.L.C.

Portfolio

Holdings
SymbolName CountrySectorIndustryMost recent quarter% of Total Shares% of Total AssetsSharesBook ValueMarket Price ValueFundamental Score 
ACHL.NASDAQAchilles Therapeutics PLC ADRUSAHealthcareBiotechnology2024-09-301.8380.038755.3k$1.8m$1m
  
  
ADCT.NYSEADC Therapeutics SAUSAHealthcareBiotechnology2024-09-301.2030.1831.1m-$1.9m$2m
  
  
AGEN.NASDAQAgenus IncUSAHealthcareBiotechnology2024-09-303.2820.212775k-$8.9m$1.5m
  
  
ALVR.NASDAQAllovir IncUSAHealthcareBiotechnology2024-09-305.6890.2676.5m$6.9m$62.6m
  
  
APLS.NASDAQApellis Pharmaceuticals IncUSAHealthcareBiotechnology2024-09-302.2643.972.8m$5.3m$71.8m
  
  
APLT.NASDAQApplied Therapeutics IncUSAHealthcareBiotechnology2024-09-301.4040.0621.6m$83.3k$882.2k
  
  
ARWR.NASDAQArrowhead Pharmaceuticals IncUSAHealthcareBiotechnology2024-12-312.322.412.9m$1.2m$43.6m
  
  
BCYC.NASDAQBicycle Therapeutics LtdUSAHealthcareBiotechnology2024-12-312.6641.1381.8m$21.1m$18.7m
  
  
BDTX.NASDAQBlack Diamond Therapeutics IncUSAHealthcareBiotechnology2024-09-301.850.0991m$1.8m$1.7m
  
  
BGNE.NASDAQBGNE.NASDAQ----0.5296.323563.3k--
  
  
CGEM.NASDAQCullinan Oncology LLCUSAHealthcareBiotechnology2024-09-302.080.6521.2m$13m$10.5m
  
  
CNTA.NASDAQCentessa Pharmaceuticals PLC ADRUSAHealthcareBiotechnology2024-12-312.2792.2243m$11.3m$49.4m
  
  
CRNX.NASDAQCrinetics Pharmaceuticals IncUSAHealthcareBiotechnology2024-09-301.7363.6361.6m$14.4m$55.1m
  
  
CYCN.NASDAQCyclerion Therapeutics IncUSAHealthcareBiotechnology2024-09-304.2860.017116.1k$351.3k$297.9k
  
  
DYN.NASDAQDyne Therapeutics IncUSAHealthcareBiotechnology2024-09-301.3241.4031.3m$9.3m$16.2m
  
  
ERAS.NASDAQErasca IncUSAHealthcareBiotechnology2024-09-303.1330.9828.8m$14.1m$13.6m
  
  
FHTX.NASDAQFoghorn Therapeutics IncUSAHealthcareBiotechnology2024-09-301.2960.15720.7k-$325.7k$3.1m
  
  
GBIO.NASDAQGeneration Bio CoUSAHealthcareBiotechnology2024-09-304.4660.142.9m$4.6m$1.5m
  
  
GLYC.NASDAQGlycoMimetics IncUSAHealthcareBiotechnology2024-12-313.0450.0171.9m$161.1k$518.7k
  
  
GOSS.NASDAQGossamer Bio IncUSAHealthcareBiotechnology2024-09-302.2990.2085.2m$1.2m$6.3m
  
  
HOOK.NASDAQHookipa Pharma IncUSAHealthcareBiotechnology2024-09-304.7010.05566.6k$3.2m$628.9k
  
  
IGMS.NASDAQIGM Biosciences IncUSAHealthcareBiotechnology2024-09-305.6010.8993.3m$4.3m$4.6m
  
  
IHS.NYSEIHS Holding LtdUSACommunication ServicesTelecom Services2024-09-300.7080.3042.3m-$1.8m$8.6m
  
  
IONQ.NYSEIONQ IncUSATechnologyComputer Hardware2024-12-310.2310.219500k$861.5k$9.3m
  
  
KRON.NASDAQKronos Bio IncUSAHealthcareBiotechnology2024-09-301.3970.035842.9k$1.5m$773.8k
  
  
KURA.NASDAQKura Oncology IncUSAHealthcareBiotechnology2024-09-301.7230.5161.3m$6.5m$9.7m
  
  
KYMR.NASDAQKymera Therapeutics IncUSAHealthcareBiotechnology2024-09-304.5855.2782.9m$34.8m$98m
  
  
LBPH.NASDAQLBPH.NASDAQ----2.3131.505903.2k--
  
  
LBPH.OTCMTKSLBPH.OTCMTKS----2.3131.505903.2k--
  
  
LXRX.NASDAQLexicon Pharmaceuticals IncUSAHealthcareBiotechnology2024-09-3010.771.27238.9m$19.2m$13.8m
  
  
NAMS.NASDAQNewAmsterdam Pharma Company N.V. Ordinary SharesUSAHealthcareBiotechnology2024-12-311.9582.3792m$14.4m$47.9m
  
  
OMGA.NASDAQOmega Therapeutics IncUSAHealthcareBiotechnology2024-09-302.3910.0441.3m$275.2k$14.5k
  
  
OVID.NASDAQOvid Therapeutics IncUSAHealthcareBiotechnology2024-09-304.0140.1182.8m$3m$1.3m
  
  
PRQR.NASDAQProQR Therapeutics BVUSAHealthcareBiotechnology2024-09-301.4870.1841.5m$403.2k$2.8m
  
  
PRTA.NASDAQProthena Corporation plcUSAHealthcareBiotechnology2024-09-302.0440.6731m$10.9m$16m
  
  
RCUS.NYSEArcus Biosciences IncUSAHealthcareBiotechnology2024-09-301.7621.2321.6m$9.9m$15.9m
  
  
RNA.NASDAQAvidity Biosciences IncUSAHealthcareBiotechnology2024-09-301.2083.3081.4m$17.5m$43.2m
  
  
RNAC.NASDAQCartesian Therapeutics Inc.USAHealthcareBiotechnology2024-09-302.2240.453572.2k$17.7k$10.3m
  
  
SEER.NASDAQSeer IncUSAHealthcareBiotechnology2024-09-306.7840.4084m$22.5m$7.6m
  
  
SLDB.NASDAQSolid Biosciences LLCUSAHealthcareBiotechnology2024-09-309.2390.6633.7m$8.2m$19m
  
  
SLN.NASDAQSilence Therapeutics PLCUSAHealthcareBiotechnology2024-09-305.9980.8612.8m$2.4m$12.7m
  
  
SRRK.NASDAQScholar Rock Holding CorpUSAHealthcareBiotechnology2024-12-319.88117.669.2m$36.3m$325.1m
  
  
STOK.NASDAQStoke Therapeutics IncUSAHealthcareBiotechnology2024-09-303.7760.9752m$8.2m$15.9m
  
  
SWTX.NASDAQSpringWorks Therapeutics IncUSAHealthcareBiotechnology2024-12-311.8522.1991.3m$8.8m$66.7m
  
  
SYRS.NASDAQSyros Pharmaceuticals IncUSAHealthcareBiotechnology2024-09-309.6430.2782.5m-$732.2k$238k
  
  
TIL.NASDAQInstil Bio Inc.USAHealthcareBiotechnology2024-09-302.9490.162192.4k$5.1m$3.1m
  
  
TNGX.NASDAQTango Therapeutics IncUSAHealthcareBiotechnology2024-09-302.4240.3562.6m$5.4m$4.8m
  
  
TRVI.NASDAQTrevi Therapeutics IncUSAHealthcareBiotechnology2024-09-303.2520.5292.9m$1.6m$17.6m
  
  
TSHA.NASDAQTaysha Gene Therapies IncUSAHealthcareBiotechnology2024-12-313.2220.5056.6m$2.3m$11.3m
  
  
VERA.NASDAQVera Therapeutics IncUSAHealthcareBiotechnology2024-09-301.3231.852837.9k$3.8m$23.2m
  
  
VIGL.NASDAQVigil Neuroscience IncUSAHealthcareBiotechnology2024-09-304.8710.151.9m$4.3m$4.6m
  
  
WVE.NASDAQWave Life Sciences LtdUSAHealthcareBiotechnology2024-09-302.4592.053.7m$3.4m$35.2m
  
  

Trades

Buys
Report date: 2024-12-31
TradeCurrent
SymbolShares%Total$ RangePrice%
BCYC.NASDAQ1.8m-39.4m12-29$10.20-16.2%
PRQR.NASDAQ1.5m-5m2-5$1.814.0%
STOK.NASDAQ2m-24.5m11-15$7.95-24.5%
TRVI.NASDAQ2.9m-9.3m2-5$6.07157.2%
Report date: 2024-09-30
TradeCurrent
SymbolShares%Total$ RangePrice%
ACHL.NASDAQ755.3k-605.1k1-1$1.39120.6%
ADCT.NYSE1.1m-3.6m3-4$1.73-31.6%
AGEN.NASDAQ775k-5.8m4-19$2.05-53.5%
ALVR.NASDAQ6.5m-5m1-1$9.491,255.7%
APLS.NASDAQ2.1m-80.2m28-42$25.52-9.9%
APLT.NASDAQ1.6m-9.6m4-9$0.54-87.4%
BDTX.NASDAQ1m-5.6m4-7$1.69-57.0%
BGNE.NASDAQ563.3k-0.000-0--
CGEM.NASDAQ1.2m-21.4m16-21$8.67-44.7%
CNTA.NASDAQ3.2m-39.9m8-18$16.4794.7%
CRNX.NASDAQ1.3m-67.5m44-56$34.26-21.6%
CYCN.NASDAQ116.1k-341.1k2-4$2.5725.7%
ERAS.NASDAQ8.8m-24.9m2-3$1.54-26.7%
FHTX.NASDAQ720.7k-5.2m5-10$4.44-6.9%
GBIO.NASDAQ2.9m-7.8m2-4$0.51-75.6%
GLYC.NASDAQ1.9m-412.2k0-0$0.2670.3%
GOSS.NASDAQ13.2m-12.7m1-1$1.2259.1%
HOOK.NASDAQ566.6k-2.7m0-7$1.11131.3%
IGMS.NASDAQ3.3m-36.4m6-23$1.39-77.5%
IHS.NYSE2.3m-7.2m3-4$3.6743.4%
IONQ.NYSE500k-3.8m6-10$18.70200.6%
KRON.NASDAQ842.9k-933.2k1-2$0.920.9%
KURA.NASDAQ1.3m-27.1m18-23$7.24-59.2%
KYMR.NASDAQ2.9m-131.1m29-53$33.0212.6%
LBPH.NASDAQ903.2k-0.000-0--
LBPH.OTCMTKS903.2k-0.000-0--
LXRX.NASDAQ38.9m-69.3m1-2$0.36-76.2%
OMGA.NASDAQ1.3m-2.1m1-2$0.01-99.1%
OVID.NASDAQ2.8m-2.9m1-1$0.49-32.9%
PRTA.NASDAQ1m-23.6m16-25$14.60-6.0%
RCUS.NYSE1.6m-25.4m14-19$9.90-26.8%
RNA.NASDAQ1.4m-62.5m37-49$30.04-18.0%
RNAC.NASDAQ572.2k-8.9m12-29$18.0644.7%
SEER.NASDAQ4m-7m2-2$1.9122.4%
SLDB.NASDAQ2.7m-22.2m6-10$5.09-11.2%
SLN.NASDAQ2.8m-52.6m15-22$4.50-70.5%
SRRK.NASDAQ11.2m-98.8m8-10$35.15366.8%
SWTX.NASDAQ1.3m-51.4m30-44$48.4459.5%
SYRS.NASDAQ2.5m-9.2m1-7$0.09-93.6%
TIL.NASDAQ192.4k-4.5m10-92$16.5071.5%
TNGX.NASDAQ2.6m-24.8m7-12$1.85-74.3%
TSHA.NASDAQ4.8m-10.7m2-3$1.72-10.9%
VERA.NASDAQ837.9k-31.7m34-47$27.80-17.5%
VIGL.NASDAQ1.9m-7.3m3-5$2.34-18.8%
WVE.NASDAQ5.7m-34.1m5-10$9.3992.8%
Adds
Report date: 2024-12-31
TradeCurrent
SymbolShares%Total$ RangePrice%
APLS.NASDAQ649k29.919.5m24-36$25.524.8%
ARWR.NASDAQ442.9k18.09.1m17-27$15.06-11.7%
CRNX.NASDAQ300k22.916.7m49-63$34.26-30.8%
DYN.NASDAQ212.7k18.86.2m23-36$12.03-47.8%
NAMS.NASDAQ1.1m127.624.9m16-27$22.8847.5%
SLDB.NASDAQ1m36.45.4m4-7$5.0932.2%
TSHA.NASDAQ1.7m35.33.5m1-3$1.7244.5%
Reduces
Report date: 2024-12-31
TradeCurrent
SymbolShares%Total$ RangePrice%
CNTA.NASDAQ-254k-7.8-4.2m14-19$16.4713.7%
GOSS.NASDAQ-8m-60.8-6.9m1-1$1.2284.4%
SRRK.NASDAQ-2m-17.8-65.4m7-46$35.15420.0%
WVE.NASDAQ-1.9m-34.4-26.3m8-17$9.3919.6%

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